bioRxiv Subject Collection: Biophysics
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This feed contains articles for bioRxiv Subject Collection "Biophysics"
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Deep Learning-Enhanced TopoStats for the Automated Quantification of DNA and Complex Biomolecular Structures
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https://www.biorxiv.org/content/10.64898/2026.05.06.723223v1?rss=1
2026-05-07doi:10.64898/2026.05.06.723223Cold Spring Harbor Laboratory2026-05-07
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UTag, a cysteine-free thermostable tagging system for tracking single mRNA translation live
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https://www.biorxiv.org/content/10.64898/2026.05.06.723082v1?rss=1
2026-05-07doi:10.64898/2026.05.06.723082Cold Spring Harbor Laboratory2026-05-07
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Temporal Hydrogen-Bond Network Analysis Reveals Substrate-Directed Connectivity in Dihydrofolate Reductase
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https://www.biorxiv.org/content/10.64898/2026.05.05.722848v1?rss=1
2026-05-07doi:10.64898/2026.05.05.722848Cold Spring Harbor Laboratory2026-05-07
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Structural modelling and biophysical analyses reveal a dimeric coiled-coil architecture in the FAZ10 central region of Trypanosoma brucei
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https://www.biorxiv.org/content/10.64898/2026.05.05.722045v1?rss=1
2026-05-07doi:10.64898/2026.05.05.722045Cold Spring Harbor Laboratory2026-05-07
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Epigenetic Control of Spatiotemporal Dynamics of Pancreatic Cancer Cells via Brg1-Rac1 Signaling
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https://www.biorxiv.org/content/10.64898/2026.05.04.722641v1?rss=1
2026-05-07doi:10.64898/2026.05.04.722641Cold Spring Harbor Laboratory2026-05-07
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Quantum kernel support vector machines for trabecular bone classification: comparing feature reduction strategies on synthetic micro-CT data
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https://www.biorxiv.org/content/10.64898/2026.05.04.722627v1?rss=1
2026-05-07doi:10.64898/2026.05.04.722627Cold Spring Harbor Laboratory2026-05-07
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Coupled Binding and Folding of NS2B/NS3 Protease and Linker Effects Revealed by Topology-based Modeling
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https://www.biorxiv.org/content/10.64898/2026.05.04.722635v1?rss=1
2026-05-07doi:10.64898/2026.05.04.722635Cold Spring Harbor Laboratory2026-05-07
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Nanoscale rheological heterogeneity revealed by Single Particle orientation Tracking (SPoT) of ultrashort carbon nanotubes in brain tissue
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https://www.biorxiv.org/content/10.64898/2026.05.04.721587v1?rss=1
2026-05-07doi:10.64898/2026.05.04.721587Cold Spring Harbor Laboratory2026-05-07
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ZBTB38 requires an extended N-terminal zinc finger network to read mCpG- and discriminate TpG-containing DNA sequences
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https://www.biorxiv.org/content/10.64898/2026.05.04.722763v1?rss=1
2026-05-07doi:10.64898/2026.05.04.722763Cold Spring Harbor Laboratory2026-05-07
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Cell Growth and Division Shape mRNA-Protein Correlations
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https://www.biorxiv.org/content/10.64898/2026.05.04.722628v1?rss=1
2026-05-06doi:10.64898/2026.05.04.722628Cold Spring Harbor Laboratory2026-05-06
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Extracting Parsimonious Quantitative Predictors of Biological Effectiveness from 'First-Principles' Radiobiology: Application to the Mixed-Quality Problem
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https://www.biorxiv.org/content/10.64898/2026.05.02.722446v1?rss=1
2026-05-06doi:10.64898/2026.05.02.722446Cold Spring Harbor Laboratory2026-05-06
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Time-step restrictions for numerical approximations of the Poisson-Nernst-Planck (PNP) equations
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https://www.biorxiv.org/content/10.64898/2026.04.30.721819v1?rss=1
2026-05-06doi:10.64898/2026.04.30.721819Cold Spring Harbor Laboratory2026-05-06
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Dynamics of synthetic transcriptional condensates emerge from RNA synthesis and degradation
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https://www.biorxiv.org/content/10.64898/2026.05.03.722550v1?rss=1
2026-05-05doi:10.64898/2026.05.03.722550Cold Spring Harbor Laboratory2026-05-05
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An underlying bistability sets amplitude and explains temperature compensation in the cyanobacterial circadian clock
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https://www.biorxiv.org/content/10.64898/2026.05.03.722537v1?rss=1
2026-05-05doi:10.64898/2026.05.03.722537Cold Spring Harbor Laboratory2026-05-05
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Differential histone tail citrullination by PAD Enzymes observed via NMR spectroscopy
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https://www.biorxiv.org/content/10.64898/2026.05.01.722238v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722238Cold Spring Harbor Laboratory2026-05-05
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Counting fluorescent emitters with a single photon avalanche diode array
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https://www.biorxiv.org/content/10.64898/2026.05.01.722215v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722215Cold Spring Harbor Laboratory2026-05-05
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Loop Extrusion Reversal by Condensin Motor is Mediated by Catch Bonds
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https://www.biorxiv.org/content/10.64898/2026.05.01.722258v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722258Cold Spring Harbor Laboratory2026-05-05
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Synthetic Biomolecular Condensates as Tunable Microtubule Assembly Hubs
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https://www.biorxiv.org/content/10.64898/2026.05.01.722010v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722010Cold Spring Harbor Laboratory2026-05-05
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Phylogenetic Analysis and Structural Evaluation of Staphylococcus aureus Serine-Aspartate Repeat-Containing Protein D with a Focus on Periprosthetic Joint Infection
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https://www.biorxiv.org/content/10.64898/2026.05.01.722179v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722179Cold Spring Harbor Laboratory2026-05-05
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Self-organized tiling generates tissue-scale hyperuniformity during development
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https://www.biorxiv.org/content/10.64898/2026.04.30.721955v1?rss=1
2026-05-05doi:10.64898/2026.04.30.721955Cold Spring Harbor Laboratory2026-05-05
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MACRO-MOLECULAR CROWDING FAVORS WRITHE IN UNWOUND DNA
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https://www.biorxiv.org/content/10.64898/2026.04.30.722034v1?rss=1
2026-05-05doi:10.64898/2026.04.30.722034Cold Spring Harbor Laboratory2026-05-05
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Cholesteryl Esters Modulate Lipid Droplet Rigidity and Monolayer Organization during Liver Cancer Progression
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https://www.biorxiv.org/content/10.64898/2026.05.01.722229v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722229Cold Spring Harbor Laboratory2026-05-05
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Npl4 decodes polyubiquitin length and gates D1-D2 coupling in human VCP/p97
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https://www.biorxiv.org/content/10.64898/2026.05.01.722286v1?rss=1
2026-05-05doi:10.64898/2026.05.01.722286Cold Spring Harbor Laboratory2026-05-05
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Defining state-selective lipid binding to brain GPCRs - introducing REVEAL
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https://www.biorxiv.org/content/10.64898/2026.05.01.722320v1?rss=1
1000 components), we define receptor-specific lipid-binding for two neuronal class C GPCRs. We show that agonism remodels lipid occupancy, selectively enriching a reduced repertoire of bound lipids. Plasmalogen lipids emerge as persistent binders across all conformational states of the metabotropic glycine receptor and are preferentially depleted under oxidative stress, implying a protective role at the receptor surface. These findings position lipids as dynamic regulators of both function and response to the cellular redox environment.
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Mechanics-Driven Emergence of Mesenchymal Migration Features
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https://www.biorxiv.org/content/10.64898/2026.04.30.721940v1?rss=1
2026-05-04doi:10.64898/2026.04.30.721940Cold Spring Harbor Laboratory2026-05-04
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CTGoMartini: A Python Framework for Simulating Biomolecular Conformational Transitions with Go-Martini Models
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https://www.biorxiv.org/content/10.64898/2026.04.30.721921v1?rss=1
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Condensate-Like Organization in Respiratory Aerosols Modulates the Dynamics of an Airborne Virus
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https://www.biorxiv.org/content/10.64898/2026.04.30.721971v1?rss=1
View larger version (58K):
org.highwire.dtl.DTLVardef@87cf4aorg.highwire.dtl.DTLVardef@3a2ea1org.highwire.dtl.DTLVardef@1cb5c8eorg.highwire.dtl.DTLVardef@299582_HPS_FORMAT_FIGEXP M_FIG C_FIG SynopsisRespiratory aerosols exhibit condensate-like physical properties that govern the evolution of the particle and modulate the behavior of airborne SARS-CoV-2.
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Connecting Cryo-EM and Crystallographic Views of RNA Folding through Ionic Conditions and Structural Flexibility
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https://www.biorxiv.org/content/10.64898/2026.05.02.722415v1?rss=1
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MeTAL enables multiparametric risk prediction for human KCNH2 variants
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https://www.biorxiv.org/content/10.64898/2026.04.29.721778v1?rss=1
2026-05-04doi:10.64898/2026.04.29.721778Cold Spring Harbor Laboratory2026-05-04
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In vivo elastography of the human retina using light-evoked intrinsic actuation
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https://www.biorxiv.org/content/10.64898/2026.05.01.722017v1?rss=1
2026-05-04doi:10.64898/2026.05.01.722017Cold Spring Harbor Laboratory2026-05-04